Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.40 |
| ▸ | GALR3 | O60755 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111531 | 0.99 | S1PR2 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11107134 | 0.99 | S1PR2 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11110500 | 0.99 | S1PR2 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11110174 | 0.92 | GALR3 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11109849 | 0.91 | S1PR2 (0.39) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11103481 | 0.90 | S1PR2 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11107717 | 0.90 | HTT (0.43) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11102791 | 0.89 | S1PR2 (0.41) | S1PR2S1PR1S1PR3LPAR2GALR3 | |
| SCHEMBL11109567 | 0.88 | S1PR2 (0.43) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 | |
| SCHEMBL11106779 | 0.88 | S1PR2 (0.43) | S1PR2S1PR1S1PR3LPAR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59036667-A | — | — | None | — | — | JP | disclosed |
| JP-59051257-A | — | — | None | — | — | JP | disclosed |
| JP-S5951257-A | NAPHTHYLTHIOCARBAMATE DERIVATIVE AND ITS PREPARATION | TOYO SODA MFG CO LTD | 1984-03-24 | — | — | JP | disclosed |
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| JP-S5936667-A | AMINOPYRIMIDINE DERIVATIVE | SANKYO CO LTD | 1984-02-28 | — | — | JP | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |