Perflunafene

Perflunafene

SCHEMBL11034652

C=CCC.FC1(F)C(F)(F)C(F)(F)C2(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C2(F)C1(F)F

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4901795 0.73 TSHR (0.50) TDP1TSHR
SCHEMBL5606390 0.73
SCHEMBL4950820 0.73 TSHR (0.50) TDP1TSHR
SCHEMBL10862 0.73
SCHEMBL2430668 0.73 TSHR (0.50) TDP1TSHR
SCHEMBL3814841 0.73
SCHEMBL11303058 0.69
SCHEMBL7943710 0.69
SCHEMBL9419517 0.69
Ethane SCHEMBL10985852 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4532362-A Oxidizing olefin with oxygen in reaction diluent which includes fluorocarbon in presence of catalyst containing palladium and heteropoly acid or copper, surfactant PHILLIPS PETROLEUM COMPANY (US) 1985-07-30 US disclosed
US-4448892-A PALLADIUM COMPOUND, ETEROPOLYACID OR COPPER COMPONENT, SURFACTANT PHILLIPS PETROLEUM COMPANY (US) 1984-05-15 US disclosed