Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8679223 | 1.00 | TLR4 (0.38) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL8215590 | 1.00 | TLR4 (0.38) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL4802597 | 1.00 | TLR4 (0.38) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL9501512 | 1.00 | TLR4 (0.38) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL11012872 | 0.93 | TLR4 (0.36) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL6130370 | 0.92 | CYP1A2 (0.40) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL10341950 | 0.92 | CYP1A2 (0.40) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL598587 | 0.92 | CYP1A2 (0.40) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL5836344 | 0.89 | TLR4 (0.42) | TLR4CYP1A2LMNAMAPK1HTT | |
| SCHEMBL5836340 | 0.89 | TLR4 (0.42) | TLR4CYP1A2LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59070624-A | — | — | None | — | — | JP | disclosed |
| JP-S5970624-A | TRANS, TRANS-4-ALKYL-4'-ALKYLBICYCLOHEXANES | CHISSO CORP | 1984-04-21 | — | — | JP | disclosed |