Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624727 | 0.88 | CACNA1F (0.61) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL11001327 | 0.87 | KCNH2 (0.57) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL10999874 | 0.85 | CACNA1F (0.55) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL9624942 | 0.82 | KCNH2 (0.65) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL9624814 | 0.82 | KCNH2 (0.82) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL9624970 | 0.82 | KCNH2 (0.82) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL10645811 | 0.81 | KCNH2 (0.80) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL9624943 | 0.78 | KCNH2 (0.56) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| SCHEMBL11035403 | 0.76 | ADRB3 (0.59) | KCNH2CACNA1FCHRM2ADRA2BADRA2C | |
| Methane SCHEMBL10644436 | 0.75 | KCNH2 (0.53) | KCNH2CACNA1FCHRM2ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0164865-A1 | N-(Aminoalkylphenyl)sulfonamides their preparation and therapeutic use | THE UPJOHN COMPANY (US) | 1985-12-18 | — | — | EP | claimed |