O-Xylene

O-Xylene

SCHEMBL11035539

Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C.Cc1ccccc1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 1.00
ACHE P22303 3/20 1.00
ALDH1A1 P00352 4/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA7 P43166 2/20 0.56
CA9 Q16790 2/20 0.56
CYP1A2 P05177 2/20 0.53
CYP2A6 P11509 2/20 0.53
CYP3A4 P08684 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 1/20 0.50
ALOX12 P18054 1/20 0.50
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
ESR1 P03372 1/20 0.45
TAAR1 Q96RJ0 1/20 0.43
HSD17B10 Q99714 1/20 0.43
TRPA1 O75762 1/20 0.42
CD44 P16070 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
O-Xylene SCHEMBL6898695 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL170581 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL11033471 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL2854068 1.00
O-Xylene SCHEMBL772 1.00
O-Xylene SCHEMBL11034038 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL29385454 1.00
O-Xylene SCHEMBL8216257 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL10522915 1.00 TSHR (1.00) TSHRACHEALDH1A1CA1CA2
O-Xylene SCHEMBL25403767 0.95 TSHR (0.91) TSHRACHEALDH1A1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487674-A USING RESIN AND SURFACTANT DRESSER INDUSTRIES, INC. (US) 1984-12-11 US disclosed