Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.55 |
| ▸ | LIG1 | P18858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26134815 | 0.89 | TSHR (0.69) | TSHRMAPTGAALMNAAKR1C3 | |
| SCHEMBL6272312 | 0.89 | TSHR (0.62) | TSHRMAPTGAAAKR1C3ALDH1A1 | |
| SCHEMBL10945911 | 0.89 | TSHR (0.51) | TSHRKEAP1LIG1MAPTMEN1 | |
| SCHEMBL25625121 | 0.86 | TSHR (0.60) | TSHRMAPTMEN1KMT2AGAA | |
| SCHEMBL2292722 | 0.86 | TSHR (0.74) | TSHRKEAP1KMT2AGAAALDH1A1 | |
| SCHEMBL27879975 | 0.85 | TSHR (0.58) | TSHRMAPTMEN1KMT2ARAB9A | |
| SCHEMBL28041092 | 0.84 | TSHR (0.56) | TSHRKEAP1MAPTMEN1KMT2A | |
| SCHEMBL11036287 | 0.83 | AKR1C3 (0.61) | TSHRMAPTGAAAKR1C3ALDH1A1 | |
| Butanedione SCHEMBL11340962 | 0.83 | TSHR (0.56) | TSHRMAPTGAALMNAAKR1C3 | |
| SCHEMBL27685255 | 0.82 | TSHR (0.55) | TSHRMAPTGAAAKR1C3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034722-B1 | COATING COMPOSITION AND PROCESS FOR ADHERING A CURABLE COMPOSITION TO A SUBSTRATE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1984-09-26 | — | — | EP | disclosed |