SCHEMBL11036007

SCHEMBL11036007

ONc1ccccc1Oc1ccccn1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.51
SLC1A5 Q15758 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
ALOX12 P18054 1/20 0.38
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RAB9A P51151 1/20 0.38
MEN1 O00255 1/20 0.37
MAPK10 P53779 1/20 0.37
GFER P55789 1/20 0.37
KMT2A Q03164 1/20 0.37
P2RX7 Q99572 2/20 0.36
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10435381 0.82 KDM4E (0.51) KDM4ESLC1A5SMN1; SMN2ALOX12NPC1
Hydrochloric Acid SCHEMBL9586143 0.81 KDM4E (0.50) KDM4ESLC1A5SMN1; SMN2ALOX12NPC1
SCHEMBL11138427 0.80 KDM4E (0.66) KDM4ESLC1A5SMN1; SMN2NPC1ALDH1A1
SCHEMBL11128036 0.80 KDM4E (0.47) KDM4ESLC1A5SMN1; SMN2ALOX12NPC1
SCHEMBL22470339 0.79 MAPK10 (0.61) KDM4ESMN1; SMN2ALOX12NPC1ALDH1A1
SCHEMBL30968557 0.79 MAPK10 (0.61) KDM4ESMN1; SMN2ALOX12NPC1ALDH1A1
SCHEMBL10582754 0.79 KDM4E (0.45) KDM4ESLC1A5SMN1; SMN2ALOX12NPC1
SCHEMBL10577713 0.79 CYP1A2 (0.48) KDM4ESLC1A5SMN1; SMN2ALOX12NPC1
SCHEMBL9359315 0.78 KDM4E (0.63) KDM4ESLC1A5SMN1; SMN2NPC1ALDH1A1
SCHEMBL5334067 0.76 KDM4E (0.56) KDM4ESLC1A5ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4526608-A Weed control ZOECON CORPORATION (US) 1985-07-02 US disclosed
US-4526608-A Weed control ZOECON CORPORATION (US) 1985-07-02 US disclosed