Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | GAA | P10253 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067312 | 0.87 | TP53 (0.66) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL27533944 | 0.87 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL12798165 | 0.86 | MAPT (0.56) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL8398940 | 0.86 | PTGDR2 (0.70) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL5627237 | 0.85 | PTGDR2 (0.57) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL13996745 | 0.85 | MAPT (0.70) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL14419325 | 0.82 | HPGD (0.58) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL5624016 | 0.81 | TP53 (0.59) | MAPTSMN1; SMN2GAALMNATP53 | |
| SCHEMBL25894308 | 0.81 | NPC1 (0.71) | SMN1; SMN2LMNATP53ALDH1A1TSHR | |
| SCHEMBL14419384 | 0.81 | SMN1; SMN2 (0.60) | MAPTSMN1; SMN2GAALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59181246-A | — | — | None | — | — | JP | disclosed |
| JP-S59181246-A | BENZOPHENONE DERIVATIVE | CHUGAI PHARMACEUT CO LTD | 1984-10-15 | — | — | JP | disclosed |