Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 2/20 | 0.34 |
| ▸ | F3 | P13726 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4760060 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL4759135 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL1278647 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL4757903 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL18403799 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL1278497 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL1278750 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL11658791 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL8746943 | 1.00 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AFAAH | |
| SCHEMBL735082 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59104339-A | — | — | None | — | — | JP | disclosed |
| JP-59199650-A | — | — | None | — | — | JP | disclosed |
| JP-S59199650-A | PRODUCTION OF LONG-CHAIN DIKETONE | NIPPON MINING CO LTD | 1984-11-12 | — | — | JP | disclosed |
| JP-S59104339-A | PREPARATION OF 2,15-HEXADECANEDIONE | NIPPON MINING CO LTD | 1984-06-16 | — | — | JP | disclosed |
| US-4087481-A | INJECTION MOLDING MATERIALS | THE UPJOHN COMPANY (US) | 1978-05-02 | — | — | US | disclosed |
| US-4072665-A | Polyamide from arylene diamine, isophthalic acid and alkylene dicarboxylic acid | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |