SCHEMBL1103650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1105444	0.94	TNF (0.43)	TNFKDRCYP11B1CYP11B2CYP17A1
	SCHEMBL1103671	0.91	CYP11B1 (0.44)	TNFCYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL1103614	0.91	KDR (0.45)	TNFKDRMAPK14CYP1A2MAOA
	SCHEMBL1103615	0.91	CYP17A1 (0.45)	CYP11B1CYP11B2CYP17A1CYP19A1MAPK14
	SCHEMBL1102820	0.91	TNF (0.48)	TNFCYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL1103667	0.90	TNF (0.46)	TNFCYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL1102816	0.89	CYP11B1 (0.48)	TNFCYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL23633147	0.89	CYP2A6 (0.44)	CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9
	SCHEMBL1102781	0.89	TNF (0.49)	TNFCYP11B1CYP11B2CYP17A1CYP19A1
	SCHEMBL29865394	0.89	CYP2A6 (0.44)	CYP11B1CYP11B2CYP1A2CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.