Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11365299 | 0.90 | TDP1 (0.68) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10838359 | 0.90 | TDP1 (0.68) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10838364 | 0.90 | TDP1 (0.68) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10856153 | 0.89 | TDP1 (0.55) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10856147 | 0.89 | TDP1 (0.55) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL11017181 | 0.87 | TDP1 (0.61) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL11365391 | 0.86 | MAPT (0.65) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10595646 | 0.86 | NR1I2 (0.73) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10850980 | 0.86 | TDP1 (0.54) | TDP1HSD17B10NR1I2ALDH1A1TSHR | |
| SCHEMBL10850989 | 0.86 | TDP1 (0.54) | TDP1HSD17B10NR1I2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150609-A2 | Cephalosporin antibiotics | GLAXO GROUP LIMITED (GB) | 1985-08-07 | — | — | EP | disclosed |