Urea

Urea

SCHEMBL11036664

C[Si](C)(C)O[Si](C)(C)C.NC(N)=O

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALDH1A1 P00352 1/20 0.43
OR51E2 Q9H255 1/20 0.43
ALOX15 P16050 2/20 0.38
BLM P54132 1/20 0.38
PMP22 Q01453 1/20 0.38
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydroxyamine SCHEMBL5188077 0.81
SCHEMBL8519856 0.80 TP53 (0.36)
Methyl Alcohol SCHEMBL22518036 0.76 TSHR (0.30)
SCHEMBL2343587 0.76
SCHEMBL6413 0.76
SCHEMBL3869195 0.72
SCHEMBL3864503 0.72
Urea SCHEMBL355336 0.72
SCHEMBL1059751 0.71
Helium SCHEMBL21981839 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109293923-B Flame-retardant modified silicone oil and preparation method and application thereof 黄山市强力化工有限公司 2021-01-08 CN claimed
CN-114507253-A Continuous production process of silazane 杭州四马化工科技有限公司 2022-05-17 CN disclosed
CN-109293923-B Flame-retardant modified silicone oil and preparation method and application thereof 黄山市强力化工有限公司 2021-01-08 CN disclosed
US-4518773-A \"3-Carbamoyloxy cephalosporins\ BRISTOL-MYERS COMPANY (US) 1985-05-21 US disclosed
US-4426520-A CEPHALOSPORIN ANTIBIOTICS BRISTOL-MYERS COMPANY (US) 1984-01-17 US disclosed
US-4407755-A BACTERICIDAL PENICILLINS BRISTOL-MYERS COMPANY (US) 1983-10-04 US disclosed
US-4374982-A Cepham compounds BRISTOL-MYERS COMPANY (US) 1983-02-22 US disclosed
US-4322347-A 2-Carbamoyloxymethyl-penicillin derivatives BRISTOL-MYERS COMPANY (US) 1982-03-30 US disclosed
US-4310459-A Process for producing carbamoyl substituted penams and carbamoyl substituted cephams from penicillin sulfoxide esters BRISTOL-MYERS COMPANY (US) 1982-01-12 US disclosed