Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.65 |
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | ALPL | P05186 | 2/20 | 0.65 |
| ▸ | ALPG | P10696 | 2/20 | 0.65 |
| ▸ | ALPI | P09923 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982202 | 0.98 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL5982208 | 0.98 | NPC1 (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL327807 | 0.90 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL28548286 | 0.84 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11036682 | 0.84 | KMT2A (0.67) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11036686 | 0.81 | MAPK1 (0.68) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11036683 | 0.81 | MAPK1 (0.72) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11048731 | 0.80 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11048726 | 0.80 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ALPL | |
| SCHEMBL11048735 | 0.80 | NPC1 (0.59) | NPC1RAB9AKMT2AMEN1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099014-A3 | DARK COLOURED COMPOSITION BASED ON LIQUID CRYSTALS | ASULAB S.A. (CH) | 1984-12-12 | — | — | EP | disclosed |
| EP-0099014-A2 | Dark coloured composition based on liquid crystals | ASULAB S.A. (CH) | 1984-01-25 | — | — | EP | disclosed |