Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5135717 | 1.00 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL1162237 | 1.00 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2521938 | 1.00 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL1162236 | 1.00 | TDP1 (0.42) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL7952400 | 0.98 | TDP1 (0.41) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| Hydrochloric Acid SCHEMBL7952403 | 0.98 | TDP1 (0.41) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2730560 | 0.86 | TDP1 (0.43) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL2519765 | 0.86 | TDP1 (0.43) | TDP1TSHRMAPTCACNA1BAPBA1 | |
| SCHEMBL1110727 | 0.83 | — | — | |
| SCHEMBL28496420 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0085083-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF HUMAN INSULIN | NORDISK INSULINLABORATORIUM (DK) | 1985-01-23 | — | — | EP | claimed |
| WO-1984003107-A1 | A PROCESS FOR THE PREPARATION OF HUMAN INSULIN | NORDISK INSULINLAB (DK) | 1984-08-16 | — | — | WO | claimed |
| EP-0085083-A1 | Process for the enzymatic preparation of human insulin. | NORDISK INSULINLAB (DK) | 1983-08-10 | — | — | EP | claimed |
| WO-1983000504-A1 | ENZYMATIC PREPARATION OF HUMAN INSULIN | ANDRESEN, FINN, HEDE | 1983-02-17 | — | — | WO | claimed |
| EP-0085083-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF HUMAN INSULIN | NORDISK INSULINLABORATORIUM (DK) | 1985-01-23 | — | — | EP | disclosed |
| EP-0085083-B1 | PROCESS FOR THE ENZYMATIC PREPARATION OF HUMAN INSULIN | NORDISK INSULINLABORATORIUM (DK) | 1985-01-23 | — | — | EP | disclosed |
| WO-1984003107-A1 | A PROCESS FOR THE PREPARATION OF HUMAN INSULIN | NORDISK INSULINLAB (DK) | 1984-08-16 | — | — | WO | disclosed |
| WO-1984003107-A1 | A PROCESS FOR THE PREPARATION OF HUMAN INSULIN | NORDISK INSULINLAB (DK) | 1984-08-16 | — | — | WO | disclosed |
| EP-0085083-A1 | Process for the enzymatic preparation of human insulin. | NORDISK INSULINLAB (DK) | 1983-08-10 | — | — | EP | disclosed |
| EP-0085083-A1 | Process for the enzymatic preparation of human insulin. | NORDISK INSULINLAB (DK) | 1983-08-10 | — | — | EP | disclosed |
| WO-1983000504-A1 | ENZYMATIC PREPARATION OF HUMAN INSULIN | ANDRESEN, FINN, HEDE | 1983-02-17 | — | — | WO | disclosed |
| WO-1983000504-A1 | ENZYMATIC PREPARATION OF HUMAN INSULIN | ANDRESEN, FINN, HEDE | 1983-02-17 | — | — | WO | disclosed |