Urea

Urea

SCHEMBL11037640

Cn1cc(O)nc1N.NC(N)=O

nearest known ligand 0.34

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.34
ADORA1 P30542 1/20 0.34
DAPK3 O43293 1/20 0.34
CSNK1A1 P48729 1/20 0.34
LIMK1 P53667 1/20 0.34
TNK2 Q07912 1/20 0.34
ROCK1 Q13464 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
DYRK1B Q9Y463 1/20 0.34
CCNC P24863 1/20 0.32
CDK8 P49336 1/20 0.32
TLR8 Q9NR97 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urea SCHEMBL20425228 0.96 ADORA2A (0.33) ADORA2AADORA1DAPK3CSNK1A1LIMK1
SCHEMBL16296 0.91
SCHEMBL6280996 0.91 BACE1 (0.32)
SCHEMBL8637088 0.89
SCHEMBL22157240 0.89
Hydrochloric Acid SCHEMBL1241282 0.89
SCHEMBL6474891 0.89
Bromide SCHEMBL21404082 0.89
Methyl Alcohol SCHEMBL28491792 0.89 BACE1 (0.31)
Ammonia Solution, Strong SCHEMBL28815279 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102397402-A A non-protein urea nitrogen for treating renal failure and creatinine WENBAO QU 2012-04-04 CN claimed
CN-103596609-B For controlling the equipment of patient temperature 塞拉瑟姆有限责任公司 2016-11-23 CN disclosed
CN-103191204-B Medicine composite for treating chronic kidney diseases and preparation method and application of medicine composite FAN JUNMING 2014-07-02 CN disclosed
CN-103191204-A Medicine composite for treating chronic kidney diseases and preparation method and application of medicine composite FAN JUNMING 2013-07-10 CN disclosed
CN-102302707-B Philippine flemingia kidney meprobamate pharmaceutical composition, production method thereof, and preparation thereof GUIZHOU YIBAI PHARMACEUTICAL 2013-05-15 CN disclosed
CN-102813661-A Novel application for glycyrrhetinic acid derivatives TIANJIN INST PHARM RESEARCH 2012-12-12 CN disclosed
CN-102397402-A A non-protein urea nitrogen for treating renal failure and creatinine WENBAO QU 2012-04-04 CN disclosed
EP-0152640-A2 Membrane spacer element and reciprocating dialyzer PURDUE RESEARCH FOUNDATION (US) 1985-08-28 EP disclosed
EP-0051458-A2 Reciprocating dialyzer having spacers PURDUE RESEARCH FOUNDATION (US) 1982-05-12 EP disclosed