SCHEMBL11037646

SCHEMBL11037646

O=C1CSC(=S)N1C/C=C/S(=O)(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 8/20 0.49
GSK3B P49841 8/20 0.49
MEN1 O00255 8/20 0.49
KMT2A Q03164 8/20 0.49
GAA P10253 5/20 0.46
ALDH1A1 P00352 5/20 0.40
RECQL P46063 4/20 0.40
MAPT P10636 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
THRB P10828 2/20 0.40
HTT P42858 2/20 0.40
POLB P06746 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HSD17B10 Q99714 2/20 0.37
LMNA P02545 1/20 0.37
TP53 P04637 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALPL P05186 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037647 1.00 GSK3A (0.49) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL8447829 0.80 GSK3A (0.54) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL181568 0.73 GSK3A (0.53) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL367565 0.70
SCHEMBL14919276 0.70 GSK3A (0.57) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL3062340 0.69 GSK3A (0.62) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL11023531 0.69 MEN1 (0.60) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL11037601 0.68 MEN1 (0.62) GSK3AGSK3BMEN1KMT2AGAA
SCHEMBL23930054 0.66
SCHEMBL6417260 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048834-B1 METHOD FOR MEASUREMENT OF TRACE ENZYMES FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
US-4404289-A REACTING A SPECTRAL SENSITIZER WITH AN ANTIBODY OR ANTIGEN, USE OF HYDRAZIDE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1983-09-13 US disclosed
US-4356244-A Quinoxaline cyanine dye sensitized organic electron donor compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-10-26 US disclosed
US-4337305-A INDOLE CYANINE DYES HAVING PHENYLSULFONYL OR BENZOYL GROUPS; LIGHT SENSITIVE ELEMENTS; ELECTROGRAPHY MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-06-29 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047472-A1 Method for immunochemical measurement of trace components FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed
US-4110116-A Fogged direct positive silver halide emulsion containing a cyanine dye having at least one benzoxazole or benzothiazole nucleus substituted with halogen atoms MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-08-29 US disclosed
US-4080496-A SENSITIZERS EASTMAN KODAK COMPANY (US) 1978-03-21 US disclosed
US-4030932-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1977-06-21 US disclosed
US-4026884-A SPECTRAL SENSITIZERS FOR SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1977-05-31 US disclosed
US-4025349-A Silver halide photographic elements spectrally sensitized with an acetylenic analog of cyanine or merocyanine dyes EASTMAN KODAK COMPANY (US) 1977-05-24 US disclosed
US-4007170-A SILVER HALIDE SENSITIZERS EASTMAN KODAK COMPANY (US) 1977-02-08 US disclosed
US-3976661-A SENSITIZERS, FILTERS EASTMAN KODAK COMPANY (US) 1976-08-24 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 US disclosed