Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038194 | 1.00 | MAPT (0.59) | MAPTALDH1A1LMNACYP2C9KMT2A | |
| SCHEMBL27516820 | 0.92 | MAPT (0.50) | MAPTALDH1A1LMNACYP2C9KMT2A | |
| SCHEMBL10810960 | 0.91 | MAPT (0.49) | MAPTALDH1A1LMNACYP2C9KMT2A | |
| SCHEMBL11043113 | 0.91 | MAPT (0.49) | MAPTALDH1A1LMNACYP2C9KMT2A | |
| SCHEMBL11038743 | 0.90 | MAPT (0.48) | MAPTALDH1A1LMNACYP2C9CYP4F2 | |
| SCHEMBL11038746 | 0.90 | MAPT (0.48) | MAPTALDH1A1LMNACYP2C9CYP4F2 | |
| SCHEMBL27497584 | 0.90 | MAPT (0.48) | MAPTALDH1A1LMNACYP2C9CYP4F2 | |
| SCHEMBL27496248 | 0.89 | CYP19A1 (0.50) | MAPTALDH1A1LMNACYP2C9CYP4F2 | |
| SCHEMBL925686 | 0.88 | CYP4F2 (0.56) | MAPTALDH1A1LMNACYP4F2CYP4A11 | |
| SCHEMBL11042574 | 0.86 | CYP2C9 (0.56) | MAPTALDH1A1LMNACYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118046-A1 | Liquid crystal compounds, liquid crystal compositions and liquid crystal display devices | HITACHI, LTD. (JP) | 1984-09-12 | — | — | EP | disclosed |