Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11018049 | 0.90 | USP2 (0.46) | PDE10AAPLNRTDP1KDM4EALDH1A1 | |
| SCHEMBL20081323 | 0.81 | PIK3CD (0.51) | PDE10AMAPTAPLNRHPGDALDH1A1 | |
| SCHEMBL10816600 | 0.78 | PDE10A (0.52) | PDE10AATM | |
| SCHEMBL1625473 | 0.75 | MEN1 (0.41) | PDE10AMEN1KMT2ATLR8POLB | |
| SCHEMBL1625073 | 0.75 | MEN1 (0.44) | MEN1LMNAKMT2ATLR8POLB | |
| SCHEMBL1625250 | 0.75 | PIK3CD (0.43) | MEN1KMT2ASMN1; SMN2TLR8POLB | |
| SCHEMBL11038035 | 0.74 | KDM4E (0.41) | HPGDKDM4EMEN1KMT2ATLR8 | |
| SCHEMBL20081212 | 0.73 | PDE10A (0.47) | PDE10AHPGDMEN1LMNAPLA2G1B | |
| SCHEMBL10816314 | 0.72 | USP2 (0.51) | PDE10AMAPTALDH1A1MEN1LMNA | |
| SCHEMBL10815373 | 0.70 | TP53 (0.44) | PDE10AMAPTAPLNRHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0138750-A1 | Process for the production of substituted benzimidazoles | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |