Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179688 | 1.00 | NR1I2 (0.53) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11038984 | 1.00 | NR1I2 (0.53) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11038988 | 1.00 | NR1I2 (0.53) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11042943 | 0.93 | NR1I2 (0.45) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11042935 | 0.93 | NR1I2 (0.45) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11042939 | 0.93 | NR1I2 (0.45) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11040725 | 0.92 | KCNH2 (0.46) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11040712 | 0.92 | KCNH2 (0.46) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11040728 | 0.92 | KCNH2 (0.46) | NR1I2ESR1PPARGPGRTDP1 | |
| SCHEMBL11040353 | 0.90 | KCNH2 (0.47) | NR1I2ESR1PPARGPGRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4381299-A | 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |
| EP-0064582-A1 | Starting compounds for preparing cephem compounds and processes for their preparation | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | disclosed |