Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DTYMK | P23919 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27775918 | 0.85 | NPC1 (0.50) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL26343205 | 0.83 | DTYMK (0.50) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL8872227 | 0.83 | MAPT (0.61) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL26343200 | 0.82 | MEN1 (0.44) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL11008714 | 0.81 | KDM4E (0.55) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL26343189 | 0.81 | DTYMK (0.48) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL26343190 | 0.81 | DTYMK (0.50) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL23458567 | 0.80 | DTYMK (0.42) | DTYMKKMT2AMEN1TTRPPOX | |
| SCHEMBL8577525 | 0.80 | KMT2A (0.44) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL14865352 | 0.79 | AR (0.48) | ALDH1A1LMNASMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034402-B1 | METHOD OF PREPARING FLUORINE-SUBSTITUTED DIPHENYL ETHER DERIVATIVES AND FLUORINE-SUBSTITUTED HALOGENO BENZENE DERIVATIVES FOR USE THEREIN | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-08-29 | — | — | EP | disclosed |
| US-4384135-A | REACTING A SUBSTITUTED BENZOTRIFLUORIDE WITH A SUBSTITUTED PHENOL | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-17 | — | — | US | disclosed |
| EP-0034402-A2 | Method of preparing fluorine-substituted diphenyl ether derivatives and fluorine-substituted halogeno benzene derivatives for use therein | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-08-26 | — | — | EP | disclosed |