SCHEMBL11039738

SCHEMBL11039738

COc1cccc(C(=O)c2ccc(O)c(OC)c2O)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.58
ALOX15 P16050 3/20 0.58
ALDH1A1 P00352 2/20 0.58
KDM4E B2RXH2 2/20 0.58
MAPT P10636 2/20 0.58
HSD17B10 Q99714 2/20 0.58
MEN1 O00255 1/20 0.58
ALOX12 P18054 1/20 0.58
RECQL P46063 1/20 0.58
KMT2A Q03164 1/20 0.58
LMNA P02545 3/20 0.55
CYP1A2 P05177 2/20 0.55
PGR P06401 2/20 0.55
SLC6A2 P23975 2/20 0.55
MAPK1 P28482 2/20 0.55
CYP2C19 P33261 2/20 0.55
CYP2D6 P10635 1/20 0.55
PDE4A P27815 1/20 0.55
HRH1 P35367 1/20 0.55
HTT P42858 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25241101 0.86 HPGD (0.58) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL25381912 0.83 MAPT (0.64) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL29215654 0.82 NPC1 (0.55) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL229995 0.82 HPGD (0.79) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL19003471 0.80 HDAC1 (0.64) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL229170 0.79 HPGD (0.70) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL30374983 0.79 HPGD (0.70) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL10438211 0.79 HPGD (0.57) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL1758178 0.79 MAPT (0.52) HPGDALOX15ALDH1A1KDM4EMAPT
SCHEMBL29215760 0.78 CYP3A4 (0.60) HPGDALOX15ALDH1A1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
EP-3278795-B1 USES OF HYDROXYBENZOPHENONE IN PREPARATION OF ANTIVIRAL AND ANTITUMOR DRUGS GUANGZHOU JTREAT BIOSCI LTD (CN) 2023-08-30 EP disclosed
CN-111808233-B Halogen-free flame-retardant acrylic resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-12-11 CN disclosed
CN-111808233-A Halogen-free flame-retardant acrylic resin composition, molding compound product, preparation method and application 中国科学院宁波材料技术与工程研究所 2020-10-23 CN disclosed
US-4442019-A NON-COAGULATING CONDUCTIVE PARTICLES IN DIELECTRIC FLUID MARKS ALVIN M 1984-04-10 US disclosed