Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040053 | 1.00 | PLCG1 (0.79) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL9623847 | 0.93 | PLCG1 (0.80) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL9623844 | 0.93 | PLCG1 (0.80) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11038535 | 0.92 | TDP1 (0.66) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11319192 | 0.92 | TDP1 (0.66) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11038537 | 0.92 | TDP1 (0.66) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11319197 | 0.92 | TDP1 (0.66) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11648858 | 0.91 | PLCG1 (0.81) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11648862 | 0.91 | PLCG1 (0.81) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 | |
| SCHEMBL11040521 | 0.91 | PLCG1 (0.65) | PLCG1TDP1CTDSP1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034924-B1 | PROCESS FOR PREPARING 3-IODOMETHYL CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0034924-A2 | Process for preparing 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-09-02 | — | — | EP | disclosed |
| US-4266049-A | Process for 3-iodomethyl cephalosporins | ELI LILLY AND COMPANY (US) | 1981-05-05 | — | — | US | disclosed |