Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975660 | 0.96 | TSHR (0.67) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL11042961 | 0.92 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL17728702 | 0.89 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL2774680 | 0.85 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL27805563 | 0.85 | TSHR (0.50) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL2703184 | 0.85 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL29047336 | 0.83 | TSHR (0.60) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL1906399 | 0.83 | TSHR (0.65) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL1904950 | 0.83 | TSHR (0.65) | TSHRALDH1A1SMN1; SMN2MAPTUSP2 | |
| SCHEMBL8075806 | 0.83 | TSHR (0.50) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038052-B1 | METHOD FOR THE PREPARATION OF CIS-ALKENYL BROMIDE AND ACETATE | Shin-Etsu Chemical Co., Ltd. (JP) | 1984-03-07 | — | — | EP | disclosed |
| EP-0038052-A1 | Method for the preparation of cis-alkenyl bromide and acetate | Shin-Etsu Chemical Co., Ltd. (JP) | 1981-10-21 | — | — | EP | disclosed |