Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 5/20 | 0.51 |
| ▸ | ESR1 | P03372 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | APEX1 | P27695 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038915 | 0.94 | NR1I2 (0.52) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10850224 | 0.94 | NR1I2 (0.63) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9308178 | 0.94 | NR1I2 (0.63) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9021449 | 0.94 | NR1I2 (0.63) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9121311 | 0.91 | NR1I2 (0.65) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL11045916 | 0.91 | NR1I2 (0.65) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9121308 | 0.91 | NR1I2 (0.65) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9123315 | 0.89 | NR1I2 (0.56) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL9120635 | 0.89 | NR1I2 (0.56) | NR1I2MAPTPPARGSLC22A6SLC22A8 | |
| SCHEMBL10780762 | 0.89 | NR1I2 (0.56) | NR1I2MAPTPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4381299-A | 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-26 | — | — | US | claimed |
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |
| US-4425340-A | ANTIBIOTICS, BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-01-10 | — | — | US | disclosed |
| US-4390534-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| US-4381299-A | 7-Amino-thiadiazole oxyimino derivatives of cephem and cepham compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-04-26 | — | — | US | disclosed |
| EP-0027599-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-04-29 | — | — | EP | disclosed |