Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21253747 | 0.84 | — | — | |
| SCHEMBL29254636 | 0.80 | KMT2A (0.52) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL890270 | 0.78 | — | — | |
| SCHEMBL7345624 | 0.78 | — | — | |
| SCHEMBL10117997 | 0.78 | — | — | |
| SCHEMBL4554697 | 0.77 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL23111386 | 0.76 | TSHR (0.46) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 | |
| SCHEMBL3026859 | 0.76 | — | — | |
| SCHEMBL249990 | 0.76 | — | — | |
| SCHEMBL4746818 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRMAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0051273-B1 | TRIALKYLAMINE/SULFUR DIOXIDE CATALYZED SULFENYLATION OF CARBAMATES | FMC Corporation (US) | 1985-01-02 | — | — | EP | disclosed |
| EP-0051273-A1 | Trialkylamine/sulfur dioxide catalyzed sulfenylation of carbamates | FMC Corporation (US) | 1982-05-12 | — | — | EP | disclosed |
| US-4329293-A | Trialkylamine/sulfur dioxide catalyzed sulfenylation of carbamates | FMC CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |