Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11026121 | 0.86 | TSHR (0.43) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11038208 | 0.80 | EPHX1 (0.39) | TSHREPHX1ALDH1A1 | |
| SCHEMBL14948790 | 0.79 | TSHR (0.44) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL15127565 | 0.76 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL10715864 | 0.76 | CA12 (0.43) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL6829843 | 0.76 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL3018969 | 0.76 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL5272432 | 0.76 | TSHR (0.41) | TSHRPPARDCA12CA1CA2 | |
| SCHEMBL11146152 | 0.75 | EPHX1 (0.41) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL20882708 | 0.75 | PPARD (0.44) | TSHRPPARDCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57002295-A | — | — | None | — | — | JP | disclosed |
| EP-0078766-B1 | PROCESS FOR PREPARING AMINOMETHYLPHOSPHONIC ACID | CIBA-GEIGY AG (CH) | 1985-04-17 | — | — | EP | disclosed |
| US-4368162-A | Process for producing aminomethylphosphonic acid | CIBA-GEIGY CORPORATION (US) | 1983-01-11 | — | — | US | disclosed |
| JP-S572295-A | PHOSPHONIC DERIVATIVE AND ITS PREPARATION | SHONO TATSUYA | 1982-01-07 | — | — | JP | disclosed |