Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041742 | 0.81 | F2 (0.49) | MCL1F2CFDTDP1HPRT1 | |
| SCHEMBL4629613 | 0.77 | MCL1 (0.54) | MCL1KMT2AF2CFDTDP1 | |
| SCHEMBL7485156 | 0.71 | F2 (0.58) | MCL1KMT2AF2CFDTYMS | |
| SCHEMBL11041800 | 0.69 | TYMS (0.44) | MCL1F2CFDTYMSTDP1 | |
| SCHEMBL11162537 | 0.69 | MCL1 (0.53) | MCL1KMT2AF2CFDTDP1 | |
| SCHEMBL16888357 | 0.68 | F2 (0.49) | MCL1KMT2AF2CFDKDM4E | |
| SCHEMBL6771976 | 0.68 | HPRT1 (0.59) | TDP1L3MBTL1HPRT1KDM4EALDH1A1 | |
| SCHEMBL24022934 | 0.67 | IKBKB (0.46) | KMT2AIKBKBTDP1L3MBTL1PRKDC | |
| SCHEMBL2726345 | 0.66 | KMT2A (0.68) | KMT2APRKDCHPRT1KDM4EALDH1A1 | |
| SCHEMBL3607241 | 0.65 | PRKDC (0.64) | KMT2ATDP1PRKDCKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0045892-B1 | PROCESS FOR THE PREPARATION OF PRECURSORS FOR POLYMERS CONTAINING THE OXAZOLIN-2-ONE RING, AND THEIR USE IN THE PRODUCTION OF HIGH MOLECULAR WEIGHT POLYMERS | BAYER AG (DE) | 1984-02-01 | — | — | EP | disclosed |
| US-4350781-A | Process for the preparation of polymer precursors containing oxazolin-2-one rings | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-21 | — | — | US | disclosed |
| EP-0045892-A1 | Process for the preparation of precursors for polymers containing the oxazolin-2-one ring, and their use in the production of high molecular weight polymers | BAYER AG (DE) | 1982-02-17 | — | — | EP | disclosed |