Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.58 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.58 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040894 | 1.00 | TDP1 (0.58) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11040874 | 0.90 | TDP1 (0.69) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11040869 | 0.90 | TDP1 (0.69) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11038323 | 0.89 | TDP1 (0.44) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11038320 | 0.89 | TDP1 (0.44) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11039232 | 0.89 | TDP1 (0.47) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL11039229 | 0.89 | TDP1 (0.47) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10643005 | 0.88 | TDP1 (0.43) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10643010 | 0.88 | TDP1 (0.43) | TDP1APAF1LMNATSHRAPEX1 | |
| SCHEMBL10675551 | 0.87 | TDP1 (0.63) | TDP1APAF1LMNATSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4464369-A | CEPHALOSPORINS, ANTIMICROBIALS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-07 | — | — | US | disclosed |
| EP-0088385-A2 | 7-Acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-09-14 | — | — | EP | disclosed |