Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.75 |
| ▸ | BLM | P54132 | 3/20 | 0.75 |
| ▸ | USP2 | O75604 | 3/20 | 0.75 |
| ▸ | TP53 | P04637 | 3/20 | 0.75 |
| ▸ | RECQL | P46063 | 3/20 | 0.75 |
| ▸ | LMNA | P02545 | 3/20 | 0.75 |
| ▸ | NSD2 | O96028 | 3/20 | 0.75 |
| ▸ | NPC1 | O15118 | 3/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.75 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.75 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.75 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.75 |
| ▸ | CSNK2A3 | Q8NEV1 | 3/20 | 0.75 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | TOP2A | P11388 | 2/20 | 0.75 |
| ▸ | MTOR | P42345 | 2/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11275434 | 1.00 | MEN1 (0.75) | MEN1KMT2AMAPK1TDP1BLM | |
| Hydrochloric Acid SCHEMBL11275683 | 0.98 | BLM (0.76) | MEN1KMT2AMAPK1TDP1BLM | |
| Hydrochloric Acid SCHEMBL10524280 | 0.98 | BLM (0.76) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL10962752 | 0.95 | MEN1 (0.67) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL3288814 | 0.95 | MEN1 (0.67) | MEN1KMT2AMAPK1TDP1BLM | |
| Hydrochloric Acid SCHEMBL10524932 | 0.94 | MEN1 (0.68) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL10633317 | 0.88 | MEN1 (0.75) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL15703039 | 0.87 | MEN1 (0.57) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL10619827 | 0.87 | MEN1 (0.57) | MEN1KMT2AMAPK1TDP1BLM | |
| SCHEMBL13194388 | 0.87 | MEN1 (0.57) | MEN1KMT2AMAPK1TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456552-A | CHELATION, ANTITUMOR | AMERICAN CYANAMID COMPANY (US) | 1984-06-26 | — | — | US | claimed |