Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.49 |
| ▸ | TYMP | P19971 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 5/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | MAP3K8 | P41279 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11749416 | 0.96 | PTGDR2 (0.50) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11753193 | 0.96 | PTGDR2 (0.50) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11753168 | 0.95 | PPARD (0.46) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11753504 | 0.95 | PPARD (0.46) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11754318 | 0.94 | PPARD (0.48) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11751668 | 0.94 | PPARD (0.45) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11751302 | 0.94 | PPARD (0.45) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11751327 | 0.94 | PTGDR2 (0.47) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11752962 | 0.94 | PPARD (0.45) | PPARDTYMPPPARGPPARAPTGDR2 | |
| SCHEMBL11751440 | 0.94 | PPARD (0.45) | PPARDTYMPPPARGPPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | claimed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | claimed |
| US-4451471-A | Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4051250-A | OXAZOLE, THIAZOLE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-09-27 | — | — | US | disclosed |
| US-3933840-A | ANTIPHLOGISTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1976-01-20 | — | — | US | disclosed |