SCHEMBL11041758

SCHEMBL11041758

CC(=O)/C1=C\CCCCCCCCCC1

nearest known ligand 0.55

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HDAC2 Q92769 4/20 0.55
HDAC4 P56524 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
CTSK P43235 1/20 0.53
HDAC1 Q13547 3/20 0.47
HDAC3 O15379 2/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
CCR2 P41597 1/20 0.37
ALDH1A1 P00352 3/20 0.34
RAB9A P51151 2/20 0.34
GSTP1 P09211 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL621702 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11247934 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11041761 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11036333 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL1229915 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11041765 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11036334 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL11038707 1.00 HDAC2 (0.55) HDAC2HDAC4HDAC8HDAC6CTSK
SCHEMBL310711 0.98
SCHEMBL720598 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4393245-A 1-ACETYL-1-CYCLODODECENE BASF AKTIENGESELLSCHAFT (DE) 1983-07-12 US claimed
EP-0051240-B1 ACETYLCYCLOUNDECANE AND ACETYLCYCLOUNDECENE, THEIR APPLICATION AND PERFUMED COMPOSITIONS CONTAINING THEM Henkel Kommanditgesellschaft auf Aktien (DE) 1984-10-10 EP disclosed
US-4393245-A 1-ACETYL-1-CYCLODODECENE BASF AKTIENGESELLSCHAFT (DE) 1983-07-12 US disclosed
EP-0051240-A1 Acetylcycloundecane and acetylcycloundecene, their application and perfumed compositions containing them Henkel Kommanditgesellschaft auf Aktien (DE) 1982-05-12 EP disclosed