Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043429 | 1.00 | HTT (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11042882 | 1.00 | HTT (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11041500 | 1.00 | HTT (0.50) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL11038680 | 0.98 | HTT (0.46) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL4493298 | 0.93 | HTT (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL7637944 | 0.93 | MEN1 (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL4497954 | 0.89 | HTT (0.48) | HTTTHRBMEN1KMT2AMAPT | |
| SCHEMBL198612 | 0.86 | TSHR (0.44) | THRBMAPTUSP2TSHR | |
| SCHEMBL980876 | 0.86 | TSHR (0.44) | THRBMAPTUSP2TSHR | |
| SCHEMBL199912 | 0.86 | TSHR (0.44) | THRBMAPTUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477447-A | ANTIBIOTIC, BACTERICIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-16 | — | — | US | disclosed |