Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.33 |
| ▸ | HMGCR | P04035 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384813 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL4355698 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL2734276 | 0.88 | TSHR (0.65) | TSHRHIF1AFAAHTRPV1PTPN7 | |
| SCHEMBL2734169 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL2734292 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL1300728 | 0.88 | TSHR (0.65) | TSHRHIF1AFAAHTRPV1PTPN7 | |
| SCHEMBL28013202 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL19432892 | 0.88 | TSHR (0.73) | TSHRFAAHTRPV1PTPN7HMGCR | |
| SCHEMBL31336313 | 0.85 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1RAB9A | |
| SCHEMBL18803990 | 0.85 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065319-B1 | PROCESS FOR THE PREPARATION OF AN UNSATURATED MACROCYCLIC KETONE | FIRMENICH SA (CH) | 1984-10-17 | — | — | EP | disclosed |
| EP-0065319-A1 | Process for the preparation of an unsaturated macrocyclic ketone | FIRMENICH SA (CH) | 1982-11-24 | — | — | EP | disclosed |
| US-4346023-A | FLAVORS, PERFUMES | FIRMENICH SA (CH) | 1982-08-24 | — | — | US | disclosed |
| US-4302607-A | CYCLOPENTADECANONES | FIRMENICH SA (CH) | 1981-11-24 | — | — | US | disclosed |
| EP-0015412-A2 | Unsaturated macrocyclic ketones; their preparation; preparation of saturated macrocyclic ketones; application in perfume and flavour compositions of some unsaturated macrocyclic ketones | FIRMENICH SA (CH) | 1980-09-17 | — | — | EP | disclosed |