SCHEMBL11042906

SCHEMBL11042906

CCC(O)C(C)(CC)CC(C)C

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.46
CYP2C19 P33261 1/20 0.30
GRIN1 Q05586 4/20 0.30
GRIN2A Q12879 4/20 0.30
GRIN2D O15399 3/20 0.30
GRIN2C Q14957 3/20 0.30
GRIN2B Q13224 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28993590 0.82 TSHR (0.58) TSHR
SCHEMBL12014993 0.80 TSHR (0.50) TSHRCYP2C19GRIN1GRIN2AGRIN2D
SCHEMBL14847330 0.80 TSHR (0.32) TSHR
SCHEMBL11038466 0.80 TSHR (0.32) TSHR
Ammonia Solution, Strong SCHEMBL15610994 0.79 TSHR (0.55) TSHR
SCHEMBL7248980 0.75 TSHR (0.50) TSHR
SCHEMBL28967871 0.74 TSHR (0.32) TSHR
SCHEMBL14508450 0.73 TSHR (0.48) TSHRCYP2C19GRIN1GRIN2AGRIN2D
SCHEMBL11043766 0.73 TSHR (0.48) TSHR
SCHEMBL10526 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0038471-B1 BETA-GAMMA-UNSATURATED KETONES AND ISOPRENOIC DIENONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PERFUME COMPOUNDS AND FLAVOURINGS Consortium für elektrochemische Industrie GmbH (DE) 1984-11-14 EP disclosed
US-4385185-A β-γ-Unsaturated ketones and isoprenoid 2,6 diones, a process for producing the same and their use as fragrant and flavoring substances CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) 1983-05-24 US disclosed
EP-0038471-A1 Beta-gamma-unsaturated ketones and isoprenoic dienones, process for their preparation and their use as perfume compounds and flavourings Consortium für elektrochemische Industrie GmbH (DE) 1981-10-28 EP disclosed