SCHEMBL11043347

SCHEMBL11043347

CC(C)=C([SiH3])Cn1cncn1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 6/20 0.40
EGLN3 Q9H6Z9 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
FDPS P14324 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7467004 0.79
SCHEMBL16402219 0.75
SCHEMBL5746694 0.75
SCHEMBL11235993 0.72 CYP19A1 (0.40) CYP19A1EGLN3CYP1A2CYP3A4CYP2D6
SCHEMBL10508172 0.70 EGLN3 (0.45) CYP19A1EGLN3CYP1A2CYP3A4CYP2D6
SCHEMBL5899076 0.70 EGLN3 (0.55) CYP19A1EGLN3CYP1A2CYP3A4CYP2D6
SCHEMBL22234928 0.67
SCHEMBL21233106 0.67 CYP1A2 (0.48) EGLN3CYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL9363949 0.67 CYP19A1 (0.40) CYP19A1EGLN3CYP1A2CYP3A4CYP2D6
SCHEMBL3232702 0.67 MEN1 (0.50) EGLN3CYP1A2CYP3A4CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148026-A2 Fungicidal imidazoles and triazoles E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-10 EP disclosed