Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11043841 | 1.00 | MEN1 (0.49) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6462690 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL20343290 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7509846 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL6462682 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7902520 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL9498967 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL7902526 | 0.96 | MEN1 (0.52) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL261024 | 0.91 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 | |
| SCHEMBL1658450 | 0.91 | MEN1 (0.56) | MEN1MAPK1KMT2ACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58032856-A | — | — | None | — | — | JP | disclosed |
| US-4439340-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1984-03-27 | — | — | US | disclosed |
| JP-S5832856-A | 4-CYANO-4'-(TRANS 4\"-(TRANS-4'''-ALKYLCYCLOHEXYL) CYCLOHEXYL)BIPHENYL | CHISSO CORP | 1983-02-25 | — | — | JP | disclosed |