Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2786880 | 0.77 | TP53 (0.59) | SMN1; SMN2TP53NPC1RAB9APOLB | |
| SCHEMBL3997590 | 0.73 | GAA (0.60) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL9142414 | 0.73 | GAA (0.60) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL6051576 | 0.73 | GAA (0.60) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| Hydrochloric Acid SCHEMBL7776978 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| Hydrochloric Acid SCHEMBL9108028 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL9225979 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL9225992 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| Ammonia Solution, Strong SCHEMBL9414597 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| Hydrochloric Acid SCHEMBL7776981 | 0.72 | GAA (0.59) | SMN1; SMN2NPC1RAB9APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4476123-A | Antibiotic derivatives, derived from cephalosporins with thiazolyl substituents, pharmaceutical preparations and salts thereof | SANOFI (FR) | 1984-10-09 | — | — | US | disclosed |