Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL11778558 | 0.92 | TDP1 (0.51) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| Adipic Acid SCHEMBL11787446 | 0.90 | TDP1 (0.49) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| SCHEMBL2204656 | 0.89 | TDP1 (0.61) | TDP1LMNAESR1ESR2MAPT | |
| Sebacic Acid SCHEMBL11781777 | 0.89 | TDP1 (0.50) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| Terephthalic Acid SCHEMBL5611007 | 0.88 | TDP1 (0.65) | TDP1HDAC6LMNAMAPT | |
| SCHEMBL9016065 | 0.88 | TDP1 (0.59) | TDP1PPARAHDAC6LMNASMN1; SMN2 | |
| SCHEMBL15154969 | 0.87 | TDP1 (0.53) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| Adipic Acid SCHEMBL12078826 | 0.87 | TDP1 (0.53) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| SCHEMBL11389878 | 0.87 | TDP1 (0.53) | TDP1LTB4RPPARAHDAC6HDAC3 | |
| SCHEMBL10911254 | 0.87 | TDP1 (0.45) | TDP1LTB4RPPARAHDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419476-A | ISOCYANATE-CAPPED POLYOL POLYURETHANE | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-12-06 | — | — | US | claimed |
| EP-0102312-A1 | Unsaturated polyurethanes | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |