Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920980 | 0.98 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1970581 | 0.94 | KDM4E (0.57) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1109842 | 0.88 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7237460 | 0.82 | KDM4E (0.61) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7205352 | 0.81 | KDM4E (0.60) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1246531 | 0.81 | KDM4E (0.56) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL12885024 | 0.80 | KDM4E (0.69) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1547822 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL20503253 | 0.79 | KDM4E (0.63) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL4025477 | 0.79 | KDM4E (0.54) | KDM4ESMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |