Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.60 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.60 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.60 |
| ▸ | ALB | P02768 | 1/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11039500 | 0.91 | MAPT (0.56) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10676259 | 0.87 | NR1I2 (0.67) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9155728 | 0.86 | NR1I2 (0.64) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10782258 | 0.86 | NR1I2 (0.64) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL9155732 | 0.86 | NR1I2 (0.64) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11039905 | 0.86 | TDP1 (0.53) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11039908 | 0.86 | TDP1 (0.53) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10646051 | 0.85 | TDP1 (0.51) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL10646048 | 0.85 | TDP1 (0.51) | NR1I2MAPTSLC22A6SLC22A8SLC22A11 | |
| SCHEMBL11040874 | 0.84 | TDP1 (0.69) | MAPTTDP1L3MBTL1TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | claimed |
| US-4463003-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-07-31 | — | — | US | disclosed |