Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27950853 | 1.00 | — | — | |
| Acetic Acid SCHEMBL10615343 | 0.96 | FFAR3 (0.50) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL14125983 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL30343482 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL896834 | 0.96 | — | — | |
| Acetic Acid SCHEMBL361746 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL28017923 | 0.96 | FFAR3 (0.58) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL514970 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA | |
| Acetic Acid SCHEMBL21145157 | 0.92 | — | — | |
| Acetic Acid SCHEMBL6150066 | 0.92 | FFAR3 (0.54) | FFAR3LCKFYNALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121492-A1 | Galvanic bath for the electroplating of a gold-copper-cadmium alloy, process for using it and article resulting from the process | Emmenegger, Heinz (CH) | 1984-10-10 | — | — | EP | disclosed |