SCHEMBL11045272

SCHEMBL11045272

CCOC(=O)C=C1CC(C)CC(C)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.46
HCAR2 Q8TDS4 1/20 0.37
HPGD P15428 3/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
NPSR1 Q6W5P4 1/20 0.36
RECQL P46063 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
CTDSP1 Q9GZU7 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
RELA Q04206 1/20 0.34
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15369698 0.93 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5690699 0.85 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5084406 0.85 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5690516 0.85 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL8334688 0.85 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5084409 0.85 ESR2 (0.48) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5690194 0.83 ESR2 (0.54) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL8335098 0.83 ESR2 (0.54) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5690198 0.83 ESR2 (0.54) ESR2HCAR2HPGDMAPK1HSD17B10
SCHEMBL5690202 0.83 ESR2 (0.54) ESR2HCAR2HPGDMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4457862-A DIKETONE PERFUMES GIVAUDAN CORPORATION (US) 1984-07-03 US disclosed