Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentadecane SCHEMBL28629536 | 0.87 | SPHK2 (0.62) | SPHK2SPHK1TSHRTHRBMEN1 | |
| Methylamine SCHEMBL16858957 | 0.79 | TSHR (0.53) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL5571338 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL33335 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL11100623 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL307959 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL5575232 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL5574655 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL20610044 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 | |
| SCHEMBL5273324 | 0.79 | TSHR (0.61) | TSHRTHRBMEN1KMT2ADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435381-A | ANTICARIES AGENTS, MOUTHWASHES | THE DOW CHEMICAL COMPANY (US) | 1984-03-06 | — | — | US | disclosed |