Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 4/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTGIR | P43119 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11398615 | 1.00 | PDE4D (0.37) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11046420 | 1.00 | PDE4D (0.37) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11381032 | 0.86 | PDE4D (0.37) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11250679 | 0.84 | PTGER2 (0.40) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11250676 | 0.84 | PTGER2 (0.40) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL11245406 | 0.84 | — | — | |
| SCHEMBL11245403 | 0.84 | — | — | |
| SCHEMBL11245401 | 0.84 | — | — | |
| SCHEMBL11389584 | 0.80 | PTGER3 (0.34) | PDE4DPTGER3PTGER4ALDH1A1KDM4E | |
| SCHEMBL10974182 | 0.80 | PDE4D (0.47) | PDE4DPTGER4ALDH1A1KDM4EHKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038613-B1 | NOVEL PROSTAGLANDINS E1 AND ANTI-THROMBOTIC COMPOSITIONS CONTAINING THEM | TEIJIN LIMITED (JP) | 1984-08-29 | — | — | EP | disclosed |
| US-4315032-A | ANTITHROMBOGENIC AGENTS, ANTIULCER AGENTS | TEITIN LIMITED (JP) | 1982-02-09 | — | — | US | disclosed |