Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 15/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046456 | 1.00 | CYSLTR1 (0.58) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11047613 | 0.92 | CYSLTR2 (0.66) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11047617 | 0.92 | CYSLTR2 (0.66) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11046723 | 0.91 | CYSLTR2 (0.68) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11047154 | 0.91 | CYSLTR2 (0.71) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11046719 | 0.91 | CYSLTR2 (0.68) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11047150 | 0.91 | CYSLTR2 (0.71) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11044571 | 0.90 | CYSLTR2 (0.67) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11047159 | 0.90 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11044575 | 0.90 | CYSLTR2 (0.67) | CYSLTR1CYSLTR2KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028063-B1 | PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLAXO GROUP LIMITED (GB) | 1984-06-13 | — | — | EP | disclosed |