Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 11/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.50 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 10/20 | 0.49 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046776 | 1.00 | TDP1 (0.54) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL11113124 | 0.92 | TDP1 (0.55) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL11008368 | 0.92 | TDP1 (0.54) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL11008363 | 0.92 | TDP1 (0.54) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL11113127 | 0.92 | TDP1 (0.55) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL11358684 | 0.92 | TDP1 (0.52) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL14304225 | 0.91 | TDP1 (0.63) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL10981094 | 0.91 | TDP1 (0.63) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL10981088 | 0.91 | TDP1 (0.63) | TDP1HSD17B10LMNAKDM4EMEN1 | |
| SCHEMBL9197195 | 0.91 | TDP1 (0.63) | TDP1HSD17B10LMNAKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487767-A | BACTERIOSTATS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4366153-A | CEPHALOSPORINS; ANTIBIOTICS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |
| US-4341775-A | CEPHALOSPORINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-07-27 | — | — | US | disclosed |
| US-4220761-A | 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-09-02 | — | — | US | disclosed |