Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.85 |
| ▸ | USP2 | O75604 | 4/20 | 0.85 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.85 |
| ▸ | PGR | P06401 | 4/20 | 0.85 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.85 |
| ▸ | AR | P10275 | 2/20 | 0.85 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.85 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.85 |
| ▸ | CNR1 | P21554 | 1/20 | 0.85 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.85 |
| ▸ | LMNA | P02545 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.81 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.81 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.81 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.81 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.81 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.81 |
| ▸ | MLNR | O43193 | 1/20 | 0.81 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047288 | 1.00 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| SCHEMBL11047296 | 1.00 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL24581289 | 0.93 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354253 | 0.93 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL102219 | 0.93 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354250 | 0.93 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone 17-Monopropionate SCHEMBL10354251 | 0.93 | CYP3A4 (0.85) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone Dipropionate SCHEMBL6055708 | 0.92 | CYP3A4 (1.00) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone Dipropionate SCHEMBL10493593 | 0.92 | CYP3A4 (1.00) | CYP3A4USP2NR3C1PGRADORA3 | |
| Beclomethasone Dipropionate SCHEMBL5095 | 0.92 | CYP3A4 (1.00) | CYP3A4USP2NR3C1PGRADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427591-A | TOPICAL ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1984-01-24 | — | — | US | disclosed |
| US-4336200-A | 17α-Acyloxy-5β-corticoids | THE UPJOHN COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4318853-A | ANTIINFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1982-03-09 | — | — | US | disclosed |