SCHEMBL11047386

SCHEMBL11047386

CC(O)CN(CC(C)O)C(C)C#N

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
DPP4 P27487 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2560546 0.79 CYP1A2 (0.44) TSHRCYP1A2MAPK1
SCHEMBL298413 0.70
SCHEMBL11047381 0.70 MAPT (0.33) TSHRDPP4
SCHEMBL6136617 0.69 TSHR (0.39) TSHRTDP1
SCHEMBL2091211 0.69 TSHR (0.39) TSHRTDP1
SCHEMBL21203188 0.69 TSHR (0.39) TSHRTDP1
SCHEMBL1144945 0.69 TSHR (0.39) TSHRTDP1
SCHEMBL16580145 0.69 CYP1A2 (0.44) TSHRCYP1A2MAPK1DPP4
SCHEMBL1582129 0.69 CYP1A2 (0.44) TSHRCYP1A2MAPK1DPP4
Hydrochloric Acid SCHEMBL10492850 0.69 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0025142-B1 POLYQUATERNARY AMMONIUM COMPOUNDS, THEIR PREPARATION, THEIR USE IN PAPER MANUFACTURING AND PAPER TREATING AGENTS CONTAINING THEM BAYER AG (DE) 1984-08-08 EP disclosed
US-4423194-A IMIDATION OF COPOLYMERS OF MALEIC ANHYDRIDE AND AN OLEFIN WITH AN AMINE BAYER AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0025142-A1 Polyquaternary ammonium compounds, their preparation, their use in paper manufacturing and paper treating agents containing them BAYER AG (DE) 1981-03-18 EP disclosed