Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11050573 | 1.00 | KMT2A (0.49) | KMT2AACECHRM2CHRM4CHRM1 | |
| SCHEMBL11046949 | 0.91 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11047709 | 0.91 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11049196 | 0.91 | KMT2A (0.55) | KMT2AACE | |
| SCHEMBL11046959 | 0.90 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11049755 | 0.90 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11046956 | 0.90 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11048405 | 0.90 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11049758 | 0.90 | KMT2A (0.54) | KMT2AACE | |
| SCHEMBL11051577 | 0.89 | ACE (0.47) | ACECHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461896-A | 1-[Acylthio) and (mercapto)-1-oxoalkyl]-1,2,3,4-tetrahydroquinoline-2-carboxylic acids | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1984-07-24 | — | — | US | disclosed |