Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | MMP17 | Q9ULZ9 | 1/20 | 0.47 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.46 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.43 |
| ▸ | MMP13 | P45452 | 2/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2495393 | 0.85 | KMT2A (0.57) | MMP2MMP3MMP8MMP14MMP17 | |
| SCHEMBL11042537 | 0.83 | KMT2A (0.47) | MMP2MMP3MMP8MMP14MMP17 | |
| SCHEMBL11070824 | 0.82 | KMT2A (0.49) | KMT2AAKR1B1AKR1A1HTR2AHTR2C | |
| SCHEMBL2497429 | 0.80 | CBX7 (0.52) | KCNQ3KCNQ2KCNQ4KCNMA1KCNQ5 | |
| SCHEMBL2497604 | 0.80 | KMT2A (0.51) | MMP2MMP3MMP8MMP14MMP17 | |
| SCHEMBL5982243 | 0.80 | KCNQ3 (0.46) | MMP2MMP3MMP8MMP14MMP17 | |
| SCHEMBL2499035 | 0.79 | KMT2A (0.53) | KCNQ3KCNQ2KCNQ4KCNMA1KCNQ5 | |
| SCHEMBL5860255 | 0.79 | KMT2A (0.50) | KCNQ3KCNQ2KCNQ4KCNMA1KCNQ5 | |
| SCHEMBL5857998 | 0.79 | KMT2A (0.53) | MMP2MMP3MMP8MMP14MMP17 | |
| SCHEMBL5858048 | 0.79 | KMT2A (0.50) | MMP2MMP3MMP8MMP14MMP17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454320-A | Process for 5-substituted dialuric acids | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |